Nitric oxide represses the proliferation of Caco-2 cells by inducing S-G(2)/M cell cycle arrest

There is conflicting data regarding the ability of nitric oxide (NO) to promote or inhibit colorectal cancer cell proliferation. Furthermore, NO reacts rapidly with endogenous superoxide at a diffusion-controlled rate to give peroxynitrite (ONOO(-)), a strong oxidant and nitrating agent. The aim of...

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Detalles Bibliográficos
Publicado en:Int J Physiol Pathophysiol Pharmacol
Main Authors: Sakuma, Satoru, Ikeda, Yukino, Inoue, Itsumi, Yamaguchi, Kanna, Honkawa, Shohko, Kohda, Tetsuya, Minamino, Saaya, Fujimoto, Yohko
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2019
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872484/
https://ncbi.nlm.nih.gov/pubmed/31777644
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