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A population of bang-bang switches of defective interfering particles makes within-host dynamics of dengue virus controllable

The titre of virus in a dengue patient and the duration of this viraemia has a profound effect on whether or not a mosquito will become infected when it feeds on the patient and this, in turn, is a key driver of the magnitude of a dengue outbreak. The assessment of the heterogeneity of viral dynamic...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Mapder, Tarunendu, Clifford, Sam, Aaskov, John, Burrage, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872170/
https://ncbi.nlm.nih.gov/pubmed/31710599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006668
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