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Combined Treatment Modalities for High-Energy Proton Irradiation: Exploiting Specific DNA Repair Dependencies

DNA repair deficiencies and genome instability are common features and hallmarks of cancer and are ubiquitously found in the full spectrum of malignant diseases. Heritable DNA repair deficiencies, for example, due to BRCA1 and BRCA2 mutations, and subsequent loss of heterozygosity in mammary, ovaria...

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Podrobná bibliografie
Vydáno v:Int J Part Ther
Hlavní autoři: Deycmar, Simon, Pruschy, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Particle Therapy Co-operative Group 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871601/
https://ncbi.nlm.nih.gov/pubmed/31773025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14338/IJPT-18-00020.1
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