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Molecular Signaling in Response to Charged Particle Exposures and its Importance in Particle Therapy

Energetic, charged particles elicit an orchestrated DNA damage response (DDR) during their traversal through healthy tissues and tumors. Complex DNA damage formation, after exposure to high linear energy transfer (LET) charged particles, results in DNA repair foci formation, which begins within seco...

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Pubblicato in:Int J Part Ther
Autori principali: Hellweg, Christine E., Chishti, Arif Ali, Diegeler, Sebastian, Spitta, Luis F., Henschenmacher, Bernd, Baumstark-Khan, Christa
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Particle Therapy Co-operative Group 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871585/
https://ncbi.nlm.nih.gov/pubmed/31773020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14338/IJPT-18-00016.1
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