Molecular Signaling in Response to Charged Particle Exposures and its Importance in Particle Therapy

Energetic, charged particles elicit an orchestrated DNA damage response (DDR) during their traversal through healthy tissues and tumors. Complex DNA damage formation, after exposure to high linear energy transfer (LET) charged particles, results in DNA repair foci formation, which begins within seco...

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Bibliographic Details
Published in:Int J Part Ther
Main Authors: Hellweg, Christine E., Chishti, Arif Ali, Diegeler, Sebastian, Spitta, Luis F., Henschenmacher, Bernd, Baumstark-Khan, Christa
Format: Artigo
Language:Inglês
Published: The Particle Therapy Co-operative Group 2018
Subjects:
Fundamental Radiobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6871585/
https://ncbi.nlm.nih.gov/pubmed/31773020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14338/IJPT-18-00016.1
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