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Seeking huntington disease biomarkers by multimodal, cross‐sectional basal ganglia imaging

Neurodegeneration of the striatum in Huntington disease (HD) is characterized by loss of medium‐spiny neurons, huntingtin nuclear inclusions, reactive gliosis, and iron accumulation. Neuroimaging allows in vivo detection of the macro‐ and micro‐structural changes that occur from presymptomatic stage...

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Detalhes bibliográficos
Publicado no:Hum Brain Mapp
Main Authors: Sánchez‐Castañeda, Cristina, Cherubini, Andrea, Elifani, Francesca, Péran, Patrice, Orobello, Sara, Capelli, Giovanni, Sabatini, Umberto, Squitieri, Ferdinando
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6870326/
https://ncbi.nlm.nih.gov/pubmed/22359398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.22019
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