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The burden of microstructural damage modulates cortical activation in elderly subjects with MCI and leuko‐araiosis. A DTI and fMRI study

The term leuko‐araiosis (LA) describes a common chronic affection of the cerebral white matter (WM) in the elderly due to small vessel disease with variable clinical correlates. To explore whether severity of LA entails some adaptive reorganization in the cerebral cortex we evaluated with functional...

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Bibliographic Details
Published in:Hum Brain Mapp
Main Authors: Mascalchi, Mario, Ginestroni, Andrea, Toschi, Nicola, Poggesi, Anna, Cecchi, Paolo, Salvadori, Emilia, Tessa, Carlo, Cosottini, Mirco, De Stefano, Nicola, Pracucci, Giovanni, Pantoni, Leonardo, Inzitari, Domenico, Diciotti, Stefano
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6869323/
https://ncbi.nlm.nih.gov/pubmed/23225611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.22216
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