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The burden of microstructural damage modulates cortical activation in elderly subjects with MCI and leuko‐araiosis. A DTI and fMRI study

The term leuko‐araiosis (LA) describes a common chronic affection of the cerebral white matter (WM) in the elderly due to small vessel disease with variable clinical correlates. To explore whether severity of LA entails some adaptive reorganization in the cerebral cortex we evaluated with functional...

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Bibliografiske detaljer
Udgivet i:Hum Brain Mapp
Main Authors: Mascalchi, Mario, Ginestroni, Andrea, Toschi, Nicola, Poggesi, Anna, Cecchi, Paolo, Salvadori, Emilia, Tessa, Carlo, Cosottini, Mirco, De Stefano, Nicola, Pracucci, Giovanni, Pantoni, Leonardo, Inzitari, Domenico, Diciotti, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6869323/
https://ncbi.nlm.nih.gov/pubmed/23225611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.22216
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