Role of Subunit D in Ubiquinone-Binding Site of Vibrio cholerae NQR: Pocket Flexibility and Inhibitor Resistance

[Image: see text] The ion-pumping NADH: ubiquinone dehydrogenase (NQR) is a vital component of the respiratory chain of numerous species of marine and pathogenic bacteria, including Vibrio cholerae. This respiratory enzyme couples the transfer of electrons from NADH to ubiquinone (UQ) to the pumping...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Raba, Daniel A., Yuan, Ming, Fang, Xuan, Menzer, William M., Xie, Bing, Liang, Pingdong, Tuz, Karina, Minh, David D. L., Juárez, Oscar
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2019
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868883/
https://ncbi.nlm.nih.gov/pubmed/31763556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02707
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