Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs

Chromosome segregation errors during female meiosis are a leading cause of pregnancy loss and human infertility. The segregation of chromosomes is driven by interactions between spindle microtubules and kinetochores. Kinetochores in mammalian oocytes are subjected to special challenges: they need to...

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Publicat a:Curr Biol
Autors principals: Zielinska, Agata P., Bellou, Eirini, Sharma, Ninadini, Frombach, Ann-Sophie, Seres, K. Bianka, Gruhn, Jennifer R., Blayney, Martyn, Eckel, Heike, Moltrecht, Rüdiger, Elder, Kay, Hoffmann, Eva R., Schuh, Melina
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868511/
https://ncbi.nlm.nih.gov/pubmed/31679939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2019.09.006
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