Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program

Novel biomarkers of type 2 diabetes (T2D) and response to preventative treatment in individuals with similar clinical risk may highlight metabolic pathways that are important in disease development. We profiled 331 metabolites in 2,015 baseline plasma samples from the Diabetes Prevention Program (DP...

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Pubblicato in:Diabetes
Autori principali: Chen, Zsu-Zsu, Liu, Jinxi, Morningstar, Jordan, Heckman-Stoddard, Brandy M., Lee, Christine G., Dagogo-Jack, Samuel, Ferguson, Jane F., Hamman, Richard F., Knowler, William C., Mather, Kieren J., Perreault, Leigh, Florez, Jose C., Wang, Thomas J., Clish, Clary, Temprosa, Marinella, Gerszten, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2019
Soggetti:
Genetics/Genomes/Proteomics/Metabolomics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868469/
https://ncbi.nlm.nih.gov/pubmed/31582408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0236
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