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Impact of water hardness on oxytetracycline oral bioavailability in fed and fasted piglets
Water hardness is a critical factor that affects oxytetracycline dissolution by chelation with cations. These interactions may lead to impaired dosing and consequently decrease absorption. Moreover, feed present in gastrointestinal tract may interact with antibiotic and alter pharmacokinetic paramet...
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| Publicado en: | Vet Med Sci |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868454/ https://ncbi.nlm.nih.gov/pubmed/31282118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/vms3.185 |
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