Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus

Exposure to harmful conditions such as radiation and desiccation induce oxidative stress and DNA damage. In radiation-resistant Deinococcus bacteria, the radiation/desiccation response is controlled by two proteins: the XRE family transcriptional repressor DdrO and the COG2856 metalloprotease IrrE....

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: de Groot, Arjan, Siponen, Marina I, Magerand, Romaric, Eugénie, Nicolas, Martin-Arevalillo, Raquel, Doloy, Jade, Lemaire, David, Brandelet, Géraldine, Parcy, François, Dumas, Renaud, Roche, Philippe, Servant, Pascale, Confalonieri, Fabrice, Arnoux, Pascal, Pignol, David, Blanchard, Laurence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868357/
https://ncbi.nlm.nih.gov/pubmed/31598697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz883
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