Structural basis for phospholipase A(2)-like toxin inhibition by the synthetic compound Varespladib (LY315920)

The World Health Organization recently listed snakebite envenoming as a Neglected Tropical Disease, proposing strategies to significantly reduce the global burden of this complex pathology by 2030. In this context, effective adjuvant treatments to complement conventional antivenom therapy based on i...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Salvador, Guilherme H. M., Gomes, Antoniel A. S., Bryan-Quirós, Wendy, Fernández, Julián, Lewin, Matthew R., Gutiérrez, José María, Lomonte, Bruno, Fontes, Marcos R. M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868273/
https://ncbi.nlm.nih.gov/pubmed/31748642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53755-5
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