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Ranking of non-coding pathogenic variants and putative essential regions of the human genome
A gene is considered essential if loss of function results in loss of viability, fitness or in disease. This concept is well established for coding genes; however, non-coding regions are thought less likely to be determinants of critical functions. Here we train a machine learning model using functi...
में बचाया:
| में प्रकाशित: | Nat Commun |
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| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868241/ https://ncbi.nlm.nih.gov/pubmed/31748530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13212-3 |
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