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Mathematical modeling of the glucagon challenge test

A model for the homeostasis of glucose through the regulating hormones glucagon and insulin is described. It contains a subsystem that models the internalization of the glucagon receptor. Internalization is a mechanism in cell signaling, through which G-protein coupled receptors are taken from the s...

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Detalles Bibliográficos
Publicado en:J Pharmacokinet Pharmacodyn
Main Authors: Masroor, Saeed, van Dongen, Marloes G. J., Alvarez-Jimenez, Ricardo, Burggraaf, Koos, Peletier, Lambertus A., Peletier, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868112/
https://ncbi.nlm.nih.gov/pubmed/31571122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-019-09655-2
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