YY1 Promotes Endothelial Cell-Dependent Tumor Angiogenesis in Hepatocellular Carcinoma by Transcriptionally Activating VEGFA

Hepatocellular carcinoma (HCC) is a typical hypervascular solid tumor that requires neoangiogenesis for growth. The vascular endothelial growth factor (VEGF) is the most potent proangiogenic factor in neovascularization. The multifunctional Yin-Yang 1 (YY1) is involved in the regulation of tumor mal...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Yang, Wendong, Li, Zhongwei, Qin, Rong, Wang, Xiaorui, An, Huihui, Wang, Yule, Zhu, Yan, Liu, Yantao, Cai, Shijiao, Chen, Shuang, Sun, Tao, Meng, Jing, Yang, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868052/
https://ncbi.nlm.nih.gov/pubmed/31799179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01187
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