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Neuronal GPCR NPR-8 regulates C. elegans defense against pathogen infection

Increasing evidence indicates that infection-triggered host defenses are regulated by the nervous system. However, the precise mechanisms of this regulation are not well understood. Here, we demonstrate that neuronal G protein-coupled receptor NPR-8 negatively regulates Caenorhabditis elegans defens...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Sellegounder, Durai, Liu, Yiyong, Wibisono, Phillip, Chen, Chia-Hui, Leap, David, Sun, Jingru
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867885/
https://ncbi.nlm.nih.gov/pubmed/31799388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw4717
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