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Genome-Wide Identification of Virulence Genes in Erysipelothrix rhusiopathiae: Use of a Mutant Deficient in a tagF Homolog as a Safe Oral Vaccine against Swine Erysipelas

Swine erysipelas is caused by the Gram-positive pathogen Erysipelothrix rhusiopathiae. The swine erysipelas live vaccine in Japan, the E. rhusiopathiae Koganei 65-0.15 strain (Koganei), has been reported to cause arthritis and endocarditis. To develop a vaccine with increased safety, we used a virul...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Shimoji, Yoshihiro, Ogawa, Yohsuke, Tsukio, Manae, Shiraiwa, Kazumasa, Nishikawa, Sayaka, Eguchi, Masahiro
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867862/
https://ncbi.nlm.nih.gov/pubmed/31548316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00673-19
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