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The Combinations Chitosan-Pam(3)CSK(4) and Chitosan-Monophosphoryl Lipid A: Promising Immune-Enhancing Adjuvants for Anticaries Vaccine PAc

We previously demonstrated that recombinant protein PAc could be administered as an anticaries vaccine. However, the relatively weak immunogenicity of PAc limits its application. In the present study, we investigated the effect of two adjuvant combinations of chitosan plus Pam(3)CSK(4) (chitosan-Pam...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Bi, Yongli, Xu, Qingan, Su, Lingkai, Xu, Jiantao, Liu, Zhongfang, Yang, Ying, Tang, Hua, Li, Yuhong, Fan, Mingwen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867853/
https://ncbi.nlm.nih.gov/pubmed/31527122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00651-19
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