Cytotoxic T-Lymphocyte-Associated Antigen 4 (CTLA-4)- and Programmed Death 1 (PD-1)-Mediated Regulation of Monofunctional and Dual Functional CD4(+) and CD8(+) T-Cell Responses in a Chronic Helminth Infection

Chronic helminth infections are known to be associated with the modulation of antigen-specific T-cell responses. Strongyloides stercoralis infection is characterized by the downmodulation of antigen-specific Th1 and Th17 responses and the upregulation of Th2 and Th9 responses. Immune homeostasis is...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Rajamanickam, Anuradha, Munisankar, Saravanan, Dolla, Chandrakumar, Nutman, Thomas B., Babu, Subash
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867839/
https://ncbi.nlm.nih.gov/pubmed/31570560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00469-19
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