Prospective pilot trial with combination of propranolol with chemotherapy in patients with epithelial ovarian cancer and evaluation on circulating immune cell gene expression

OBJECTIVE: To determine the feasibility of pharmacologic beta-adrenergic blockade in women with newly diagnosed stage II-IV epithelial ovarian cancer (EOC) throughout primary treatment. METHODS: Patients initiated propranolol prior to beginning chemotherapy or surgery. Feasibility was assessed as pr...

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Udgivet i:Gynecol Oncol
Main Authors: Ramondetta, Lois M., Hu, Wei, Thaker, Premal H., Urbauer, Diana L., Chisholm, Gary B., Westin, Shannon N., Sun, Yunjie, Ramirez, Pedro T., Fleming, Nicole, Sahai, Sunil K., Nick, Alpa M., Arevalo, Jesusa M. G., Dizon, Thomas, Coleman, Robert L., Cole, Steve W., Sood, Anil K.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867685/
https://ncbi.nlm.nih.gov/pubmed/31353053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.07.004
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