Prospective pilot trial with combination of propranolol with chemotherapy in patients with epithelial ovarian cancer and evaluation on circulating immune cell gene expression

OBJECTIVE: To determine the feasibility of pharmacologic beta-adrenergic blockade in women with newly diagnosed stage II-IV epithelial ovarian cancer (EOC) throughout primary treatment. METHODS: Patients initiated propranolol prior to beginning chemotherapy or surgery. Feasibility was assessed as pr...

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Veröffentlicht in:Gynecol Oncol
Hauptverfasser: Ramondetta, Lois M., Hu, Wei, Thaker, Premal H., Urbauer, Diana L., Chisholm, Gary B., Westin, Shannon N., Sun, Yunjie, Ramirez, Pedro T., Fleming, Nicole, Sahai, Sunil K., Nick, Alpa M., Arevalo, Jesusa M. G., Dizon, Thomas, Coleman, Robert L., Cole, Steve W., Sood, Anil K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867685/
https://ncbi.nlm.nih.gov/pubmed/31353053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2019.07.004
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