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Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample

OBJECTIVE: The FKBP5 gene codes for a co‐chaperone that regulates glucocorticoid receptor sensitivity and thereby impacts the reactivity of the hypothalamic–pituitary–adrenal (HPA)‐axis. Evidence suggested that subjects exposed to childhood abuse and carrying the TT genotype of the FKBP5 gene single...

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Dettagli Bibliografici
Pubblicato in:Hum Brain Mapp
Autori principali: Grabe, Hans Jörgen, Wittfeld, Katharina, Van der Auwera, Sandra, Janowitz, Deborah, Hegenscheid, Katrin, Habes, Mohamad, Homuth, Georg, Barnow, Sven, John, Ulrich, Nauck, Matthias, Völzke, Henry, Meyer zu Schwabedissen, Henriette, Freyberger, Harald Jürgen, Hosten, Norbert
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6867563/
https://ncbi.nlm.nih.gov/pubmed/26813705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23123
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