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Genetic effect of MTHFR C677T polymorphism on the structural covariance network and white‐matter integrity in Alzheimer's disease

The 677 C to T transition in the MTHFR gene is a genetic determinant for hyperhomocysteinemia. We investigated whether this polymorphism modulates gray matter (GM) structural covariance networks independently of white‐matter integrity in patients with Alzheimer's disease (AD). GM structural cov...

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Bibliografische gegevens
Gepubliceerd in:Hum Brain Mapp
Hoofdauteurs: Chang, Yu‐Tzu, Hsu, Shih‐Wei, Tsai, Shih‐Jen, Chang, Ya‐Ting, Huang, Chi‐Wei, Liu, Mu‐En, Chen, Nai‐Ching, Chang, Wen‐Neng, Hsu, Jung‐Lung, Lee, Chen‐Chang, Chang, Chiung‐Chih
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866732/
https://ncbi.nlm.nih.gov/pubmed/28342207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23572
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