Dynamic causal modeling in PTSD and its dissociative subtype: Bottom–up versus top–down processing within fear and emotion regulation circuitry

Objective Posttraumatic stress disorder (PTSD) is associated with decreased top–down emotion modulation from medial prefrontal cortex (mPFC) regions, a pathophysiology accompanied by hyperarousal and hyperactivation of the amygdala. By contrast, PTSD patients with the dissociative subtype (PTSD + DS...

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Detalhes bibliográficos
Publicado no:Hum Brain Mapp
Main Authors: Nicholson, Andrew A., Friston, Karl J., Zeidman, Peter, Harricharan, Sherain, McKinnon, Margaret C., Densmore, Maria, Neufeld, Richard W.J., Théberge, Jean, Corrigan, Frank, Jetly, Rakesh, Spiegel, David, Lanius, Ruth A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866710/
https://ncbi.nlm.nih.gov/pubmed/28836726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23748
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