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Polycomb/Trithorax Antagonism: Cellular Memory in Stem Cell Fate and Function

Stem cells are continuously challenged with the decision to either self-renew or adopt a new fate. Self-renewal is regulated by a system of cellular memory, which must be bypassed for differentiation. Previous studies have identified Polycomb Group (PcG) and Trithorax Group (TrxG) proteins as key mo...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Brand, Marjorie, Nakka, Kiran, Zhu, Jiayu, Dilworth, F. Jeffrey
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866673/
https://ncbi.nlm.nih.gov/pubmed/30951661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.03.005
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