Effect of Caspofungin vs Fluconazole Prophylaxis on Invasive Fungal Disease Among Children and Young Adults With Acute Myeloid Leukemia: A Randomized Clinical Trial

IMPORTANCE: Children, adolescents, and young adults with acute myeloid leukemia are at high risk of life-threatening invasive fungal disease with both yeasts and molds. OBJECTIVE: To compare the efficacy of caspofungin vs fluconazole prophylaxis against proven or probable invasive fungal disease and...

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Dettagli Bibliografici
Pubblicato in:JAMA
Autori principali: Fisher, Brian T., Zaoutis, Theoklis, Dvorak, Christopher C., Nieder, Michael, Zerr, Danielle, Wingard, John R., Callahan, Colleen, Villaluna, Doojduen, Chen, Lu, Dang, Ha, Esbenshade, Adam J., Alexander, Sarah, Wiley, Joseph M., Sung, Lillian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2019
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6865545/
https://ncbi.nlm.nih.gov/pubmed/31688884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.15702
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