Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers

BACKGROUND: Mesenchymal stem cells (MSCs) have been explored as promising tools for treatment of several neurological and neurodegenerative diseases. MSCs release abundant extracellular vesicles (EVs) containing a variety of biomolecules, including mRNAs, miRNAs, and proteins. We hypothesized that E...

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Dades bibliogràfiques
Publicat a:Stem Cell Res Ther
Autors principals: Bodart-Santos, Victor, de Carvalho, Luiza R. P., de Godoy, Mariana A., Batista, André F., Saraiva, Leonardo M., Lima, Luize G., Abreu, Carla Andreia, De Felice, Fernanda G., Galina, Antonio, Mendez-Otero, Rosalia, Ferreira, Sergio T.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864996/
https://ncbi.nlm.nih.gov/pubmed/31747944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1432-5
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