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Protective Effect of Edaravone on Cyclophosphamide Induced Oxidative Stress and Neurotoxicity in Rats
BACKGROUND: Cyclophosphamide (CPA) is the most widely prescribed cancer chemotherapeutic agent which shows serious neurotoxic side effect. Generation of reactive oxygen species at the cellular level is the basic mechanism of cyclophosphamide induced neurotoxicity. Edaravone is the synthetic drug use...
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| Published in: | Curr Drug Saf |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Bentham Science Publishers
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6864589/ https://ncbi.nlm.nih.gov/pubmed/31057112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1574886314666190506100717 |
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