Genomic Analysis of Posterior Fossa Meningioma Demonstrates Frequent AKT1 E17K Mutations in Foramen Magnum Meningiomas

Objective  Posterior fossa meningiomas are surgically challenging tumors that are associated with high morbidity and mortality. We sought to investigate the anatomical distribution of clinically actionable mutations in posterior fossa meningioma to facilitate identifying patients amenable for system...

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Pubblicato in:J Neurol Surg B Skull Base
Autori principali: Williams, Sally R., Juratli, Tareq A., Castro, Brandyn A., Lazaro, Tyler T., Gill, Corey M., Nayyar, Naema, Strickland, Matthew R., Babinski, Melanie, Johnstone, Sarah E., Frosch, Matthew P., Silverman, Ian M., Ely, Heather A., Kaplan, Alexander B., D'Andrea, Megan R., Bihun, Ivanna V., Hoang, Kaitlin, Batchelor, Emily, Christiansen, Jason, Cahill, Daniel P., Barker, Frederick G., Brastianos, Priscilla K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Georg Thieme Verlag KG 2019
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864425/
https://ncbi.nlm.nih.gov/pubmed/31750041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1676821
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