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Rezafungin treatment in mouse models of invasive candidiasis and aspergillosis: Insights on the PK/PD pharmacometrics of rezafungin efficacy

Rezafungin acetate is a novel echinocandin in clinical development for prevention and treatment of invasive fungal infections. Rezafungin is differentiated by a pharmacokinetic/pharmacodynamic (PK/PD) profile that includes a long half‐life allowing once‐weekly administration, front‐loaded plasma dru...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Miesel, Lynn, Lin, Kun‐Yuan, Ong, Voon
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864408/
https://ncbi.nlm.nih.gov/pubmed/31763045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.546
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