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Islet-Specific Prmt5 Excision Leads to Reduced Insulin Expression and Glucose Intolerance in Mice

Protein arginine methyltransferase 5 (PRMT5), a symmetric arginine methyltransferase, regulates cell functions by influencing gene transcription through posttranslational modification of histones and non-histone proteins. PRMT5 interacts with multiple partners including menin, which controls beta ce...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Ma, Jian, He, Xin, Cao, Yan, O’Dwyer, Kienan, Szigety, Katherine M., Wu, Yuan, Gurung, Buddha, Feng, Zijie, Katona, Bryson W., Hua, Xianxin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864278/
https://ncbi.nlm.nih.gov/pubmed/31539871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-19-0268
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