Understanding Ciprofloxacin Failure in Pseudomonas aeruginosa Biofilm: Persister Cells Survive Matrix Disruption

Biofilms are commonly recalcitrant to antibiotics, through incompletely elucidated mechanisms such as tolerance and persistence. We aimed at investigating how a Pseudomonas aeruginosa biofilm escapes ciprofloxacin treatment. P. aeruginosa PA14 in vitro mature biofilms were challenged with supra-MIC...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Soares, Anaïs, Roussel, Valérie, Pestel-Caron, Martine, Barreau, Magalie, Caron, François, Bouffartigues, Emeline, Chevalier, Sylvie, Etienne, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864029/
https://ncbi.nlm.nih.gov/pubmed/31798554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02603
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