Aging boosts antiviral CD8(+)T cell memory through improved engagement of diversified recall response determinants

The determinants of protective CD8(+) memory T cell (CD8(+)T(M)) immunity remain incompletely defined and may in fact constitute an evolving agency as aging CD8(+)T(M) progressively acquire enhanced rather than impaired recall capacities. Here, we show that old as compared to young antiviral CD8(+)T...

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Udgivet i:PLoS Pathog
Main Authors: Davenport, Bennett, Eberlein, Jens, Nguyen, Tom T., Victorino, Francisco, Jhun, Kevin, Abuirqeba, Haedar, van der Heide, Verena, Heeger, Peter, Homann, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863560/
https://ncbi.nlm.nih.gov/pubmed/31697793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008144
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