Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer’s disease

Both aging and Alzheimer’s disease (AD) are associated with widespread epigenetic changes, with most evidence suggesting global hypomethylation in AD. It is, however, unclear how these age-related epigenetic changes are linked to molecular aberrations as expressed in animal models of AD. Here, we in...

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Publicado no:Mol Cell Neurosci
Main Authors: Lardenoije, Roy, van den Hove, Daniël L.A., Havermans, Monique, van Casteren, Anne, Le, Kevin X., Palmour, Roberta, Lemere, Cynthia A., Rutten, Bart P.F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863355/
https://ncbi.nlm.nih.gov/pubmed/29113959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2017.11.002
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