Transdermal delivery of 4-aminopyridine accelerates motor functional recovery and improves nerve morphology following sciatic nerve crush injury in mice

Oral 4-aminopyridine (4-AP) is clinically used for symptomatic relief in multiple sclerosis and we recently demonstrated that systemic 4-AP had previously unknown clinically-relevant effects after traumatic peripheral nerve injury including the promotion of re-myelination, improvement of nerve condu...

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Bibliografiske detaljer
Udgivet i:Neural Regen Res
Main Authors: Clark, Andrew R., Hsu, Chia George, Talukder, M A Hassan, Noble, Mark, Elfar, John C.
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer - Medknow 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862422/
https://ncbi.nlm.nih.gov/pubmed/31535662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1673-5374.264471
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