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Interleukin-6 Induces Myogenic Differentiation via JAK2-STAT3 Signaling in Mouse C2C12 Myoblast Cell Line and Primary Human Myoblasts

Postnatal muscle growth and exercise- or injury-induced regeneration are facilitated by myoblasts. Myoblasts respond to a variety of proteins such as cytokines that activate various signaling cascades. Cytokines belonging to the interleukin 6 superfamily (IL-6) influence myoblasts’ proliferation but...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Steyn, Paul J., Dzobo, Kevin, Smith, Robert I., Myburgh, Kathryn H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862063/
https://ncbi.nlm.nih.gov/pubmed/31652937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215273
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