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Impact of substitution registry on receptor-activation profiles of backbone-modified glucagon-like peptide-1 analogues
Family B G protein-coupled receptors play important physiological roles and possess large extracellular domains (ECD) that aid in binding the long polypeptide hormones that are their natural agonists. We have previously shown that agonist analogues in which subsets of native α-amino acid residues ar...
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| Udgivet i: | Chembiochem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6861653/ https://ncbi.nlm.nih.gov/pubmed/31172641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900300 |
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