Fungal Chitin Reduces Platelet Activation Mediated via TLR8 Stimulation

Platelets play an important role in the innate immune response. During candidaemia, circulating fungal polysaccharides, including chitin, are released into the bloodstream and can interact with platelets and induce modulation of platelet activities. However, the role of circulating chitin in platele...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Leroy, Jordan, Bortolus, Clovis, Lecointe, Karine, Parny, Melissa, Charlet, Rogatien, Sendid, Boualem, Jawhara, Samir
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Cellular and Infection Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861417/
https://ncbi.nlm.nih.gov/pubmed/31781518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00383
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