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Expression of the potential therapeutic target claudin-18.2 is frequently decreased in gastric cancer: results from a large Caucasian cohort study

Gastric cancer (GC) is frequently diagnosed and treated in advanced tumour stages with poor prognosis. Recent studies have identified isoform 2 of the tight junction protein claudin-18 (CLDN18.2) as a promising target in GC therapy. In this study, we aimed to outline the expression of CLDN18.2 and i...

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Dettagli Bibliografici
Pubblicato in:Virchows Arch
Autori principali: Dottermusch, Matthias, Krüger, Sandra, Behrens, Hans-Michael, Halske, Christine, Röcken, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861347/
https://ncbi.nlm.nih.gov/pubmed/31332522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-019-02624-7
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