Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects

OBJECTIVE: The aetiology of thoracic aortic aneurysm (TAA) is largely unknown, but inflammation is likely to play a central role in the pathogenesis. In this present study, we aim to investigate the complement receptors in TAA. METHODS: Aortic tissue and blood from 31 patients with non-syndromic TAA...

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Detalhes bibliográficos
Publicado no:Open Heart
Main Authors: Holt, Margrethe, Seim, Bjørn E, Øgaard, Jonas, Olsen, Maria B, Woldbæk, Per R, Aukrust, Pål, Yndestad, Arne, Mollnes, Tom Eirik, Nilsson, Per H, Louwe, Mieke C, Ranheim, Trine
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Aortic and Vascular Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861114/
https://ncbi.nlm.nih.gov/pubmed/31798913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2019-001098
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