A proline-rich motif on VGLUT1 reduces synaptic vesicle super-pool and spontaneous release frequency

Glutamate secretion at excitatory synapses is tightly regulated to allow for the precise tuning of synaptic strength. Vesicular Glutamate Transporters (VGLUT) accumulate glutamate into synaptic vesicles (SV) and thereby regulate quantal size. Further, the number of release sites and the release prob...

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書目詳細資料
發表在:eLife
Main Authors: Zhang, Xiao Min, François, Urielle, Silm, Kätlin, Angelo, Maria Florencia, Fernandez-Busch, Maria Victoria, Maged, Mona, Martin, Christelle, Bernard, Véronique, Cordelières, Fabrice P, Deshors, Melissa, Pons, Stéphanie, Maskos, Uwe, Bemelmans, Alexis Pierre, Wojcik, Sonja M, El Mestikawy, Salah, Humeau, Yann, Herzog, Etienne
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2019
主題:
Cell Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861006/
https://ncbi.nlm.nih.gov/pubmed/31663854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50401
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