Chemogenetic Activation of Excitatory Neurons Alters Hippocampal Neurotransmission in a Dose-Dependent Manner

Designer receptors exclusively activated by designer drugs (DREADD)-based chemogenetic tools are extensively used to manipulate neuronal activity in a cell type-specific manner. Whole-cell patch-clamp recordings indicate membrane depolarization, coupled with increased neuronal firing rate, following...

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Опубликовано в: :eNeuro
Главные авторы: Pati, Sthitapranjya, Salvi, Sonali S., Kallianpur, Mamata, Vaidya, Bhupesh, Banerjee, Antara, Maiti, Sudipta, Clement, James P., Vaidya, Vidita A.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2019
Предметы:
Methods/New Tools
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6860986/
https://ncbi.nlm.nih.gov/pubmed/31645362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0124-19.2019
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