ILDR2 Is a Novel B7-like Protein That Negatively Regulates T Cell Responses

The B7-like protein family members play critical immunomodulatory roles and constitute attractive targets for the development of novel therapies for human diseases. We identified Ig-like domain–containing receptor (ILDR)2 as a novel B7-like protein with robust T cell inhibitory activity, expressed i...

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Publicado no:J Immunol
Main Authors: Hecht, Iris, Toporik, Amir, Podojil, Joseph R., Vaknin, Ilan, Cojocaru, Gady, Oren, Anat, Aizman, Elizabeta, Liang, Spencer C., Leung, Ling, Dicken, Yosef, Novik, Amit, Marbach-Bar, Nadav, Elmesmari, Aziza, Tange, Clare, Gilmour, Ashley, McIntyre, Donna, Kurowska-Stolarska, Mariola, McNamee, Kay, Leitner, Judith, Greenwald, Shirley, Dassa, Liat, Levine, Zurit, Steinberger, Peter, Williams, Richard O., Miller, Stephen D., McInnes, Iain B., Neria, Eyal, Rotman, Galit
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6860365/
https://ncbi.nlm.nih.gov/pubmed/29431694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700325
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