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G-Quadruplex and protein binding by single-molecule FRET microscopy

G-quadruplex (G4) is a non-canonical nucleic acid structure that arises from the stacking of planar G-tetrads, stabilized by monovalent cations. G4 forming sequences exist throughout the genome and G4 structures are shown to be involved in many processes including DNA replication and gene expression...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Lee, Chun-Ying, McNerney, Christina, Myong, Sua
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859946/
https://ncbi.nlm.nih.gov/pubmed/31444758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9666-7_18
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