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The expanding role of venetoclax in chronic lymphocytic leukemia and small lymphocytic lymphoma

The BCL-2 protein family members inhibit cellular apoptosis, and their overexpression represents a common survival adaption in cancer. Recently, a selective BCL-2 inhibitor ABT-199, venetoclax, has demonstrated remarkable activity in relapsed/refractory chronic lymphocytic leukemia/small lymphocytic...

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Detalhes bibliográficos
Publicado no:Blood Lymphat Cancer
Main Authors: Schieber, Michael, Ma, Shuo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859801/
https://ncbi.nlm.nih.gov/pubmed/32009829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BLCTT.S177009
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