Development of [(18)F]FAMTO: A novel fluorine-18 labelled positron emission tomography (PET) radiotracer for imaging CYP11B1 and CYP11B2 enzymes in adrenal glands

INTRODUCTION: Primary aldosteronism accounts for 6–15% of hypertension cases, the single biggest contributor to global morbidity and mortality. Whilst ~50% of these patients have unilateral aldosterone-producing adenomas, only a minority of these have curative surgery as the current diagnosis of uni...

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Vydáno v:Nucl Med Biol
Hlavní autoři: Bongarzone, Salvatore, Basagni, Filippo, Sementa, Teresa, Singh, Nisha, Gakpetor, Caleb, Faugeras, Vincent, Bordoloi, Jayanta, Gee, Antony D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859501/
https://ncbi.nlm.nih.gov/pubmed/30578137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2018.11.002
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