Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells conserved across mammalian species, including mice and humans. By sequencing RNA from sorted MR1-5-OP-RU tetramer(+) cells derived from either human blood or murine lungs, we define the basic transcriptome of an activ...

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Udgivet i:Cell Rep
Main Authors: Hinks, Timothy S.C., Marchi, Emanuele, Jabeen, Maisha, Olshansky, Moshe, Kurioka, Ayako, Pediongco, Troi J., Meehan, Bronwyn S., Kostenko, Lyudmila, Turner, Stephen J., Corbett, Alexandra J., Chen, Zhenjun, Klenerman, Paul, McCluskey, James
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859474/
https://ncbi.nlm.nih.gov/pubmed/31533045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.07.039
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