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How kinesin waits for ATP affects the nucleotide and load dependence of the stepping kinetics

Conventional kinesin, responsible for directional transport of cellular vesicles, takes multiple nearly uniform 8.2-nm steps by consuming one ATP molecule per step as it walks toward the plus end of the microtubule (MT). Despite decades of intensive experimental and theoretical studies, there are ga...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Takaki, Ryota, Mugnai, Mauro L., Goldtzvik, Yonathan, Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859354/
https://ncbi.nlm.nih.gov/pubmed/31659052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913650116
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