Cdc42 Promotes ADSC-Derived IPC Induction, Proliferation, And Insulin Secretion Via Wnt/β-Catenin Signaling

PURPOSE: Type 1 diabetes mellitus (T1DM) is characterized by irreversible islet β cell destruction. Accumulative evidence indicated that Cdc42 and Wnt/β-catenin signaling both play a critical role in the pathogenesis and development of T1DM. Further, bio-molecular mechanisms in adipose-derived mesen...

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Publicado en:Diabetes Metab Syndr Obes
Autores principales: Xiao, Xing-Hua, Huang, Qi-Yuan, Qian, Xian-Ling, Duan, Jing, Jiao, Xue-Qiao, Wu, Long-Yuan, Huang, Qing-Yun, Li, Jun, Lai, Xing-Ning, Shi, Yu-Bo, Xiong, Li-Xia
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859340/
https://ncbi.nlm.nih.gov/pubmed/32009808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DMSO.S226055
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