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Nucleic acid cleavage with a hyperthermophilic Cas9 from an uncultured Ignavibacterium

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated 9 (Cas9) systems have been effectively harnessed to engineer the genomes of organisms from across the tree of life. Nearly all currently characterized Cas9 proteins are derived from mesophilic bacteria, and canonical Cas9...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Schmidt, Stephanie Tzouanas, Yu, Feiqiao Brian, Blainey, Paul C., May, Andrew P., Quake, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859307/
https://ncbi.nlm.nih.gov/pubmed/31659048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1904273116
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