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From Isocyanides to Iminonitriles via Silver-mediated Sequential Insertion of C(sp(3))–H Bond

Heterocycles are prevalent constituents of many marketing drugs and biologically active molecules to meet modern medical challenges. Isocyanide insertion into C(sp(3))–H bonds is challenging especially for the construction of quaternary carbon centers. Herein, we describe an efficient strategy for t...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Chi, Huiwen, Li, Hao, Liu, Bingxin, Ye, Rongxuan, Wang, Haoyang, Guo, Yin-Long, Tan, Qitao, Xu, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859232/
https://ncbi.nlm.nih.gov/pubmed/31731202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.10.057
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